That is moderately disturbing. I guess if one's going to be a villain and murder people horribly, at least getting known as "The Blood Countess" is something to show for it...?
I've got some genuine additions:
Baldwin IV of Jerusalem, the leper king. Had one of the most debilitating diseases in history, still ruled his kingdom very effectively for about six years until he was blind and couldn't walk, that period including the total loss of function in his sword-arm, which he responded to by learning to fight left handed.
Enrico Dandolo, doge of Venice at the time of the Fourth Crusade. For those who don't know, the Fourth was the one that went wrong. Really wrong. The intention was to take a Venetian fleet to Egypt and capture it with Frankish knights, but this didn't exactly happen, mostly because not enough Crusaders turned up to pay the Venetians.
The Crusade thus ended up capturing parts of the Dalmatian coast for Venice, then taking a load of Aegean islands for Venice on their way to Constantinople where in exchange for help in a coup a deposed Emperor had offered huge amounts of money, to be used to pay the Venetians. This ended with the Emperors all being overthrown and replaced with a candidate backed by Venice.
This entire episode was not masterminded by an energetic, domineering-looking doge in the prime of his life. It was masterminded by a blind eighty year old man named Enrico Dandolo. In retrospect for Europe in general and particularly Byzantium the crusade was A Bad Thing, but for the Venetians at the time they'd just pulled off the biggest trade coup in history, including pulling down an entire Empire pretty much just to open up the Black Sea trade routes, and not only this people were paying them to do it. Magnificent Bastard of history award at the very least.